Faculty of Medicine

Course Details

KTO KARATAY UNIVERSITY
Medical School
Programme of Faculty of Medicine
Course Details

Course Code	Course Name	Year	Period	Semester	T+A+L	Credit	ECTS
KURUL23	Circulatory/Respiratory System	2026	Autumn	3	158+6+48	12	12

Course Type	Compulsory
Course Cycle	Bachelor's (First Cycle) (TQF-HE: Level 6 / QF-EHEA: Level 1 / EQF-LLL: Level 6)
Course Language	Turkish
Methods and Techniques	-
Mode of Delivery	Face to Face
Prerequisites	-
Coordinator	Res. Asst. Fatma Zehra ERBAYRAM
Instructor(s)	Res. Asst. Fatma Zehra ERBAYRAM
Instructor Assistant(s)	Asst. Prof. Kaniye Zeynep ÇALIŞKAN SAK

Course Instructor(s)

Name and Surname	Room	E-Mail Address	Internal	Meeting Hours
Asst. Prof. Şerife ALPA	B BLOK-BZ02	[email protected]	7411
Res. Asst. Fatma Nur TÜRKOĞLU	B BLOK-BZ01	[email protected]	7260
Asst. Prof. Levent SARIYILDIZ	BZ-12	[email protected]	7311	Monday 10:00-11:00
Asst. Prof. Hatice Nur ŞEFLEK	B-BZ06	[email protected]	7583	Monday 10:00-11:00

Course Content

The curriculum consists of required core courses (Anatomy, Physiology, Medical Biochemistry, Medical Microbiology, Histology and Embryology, Biophysics, Clinical Practice, Evidence-Based Medicine, and Community-Based Medicine) and elective courses. Theoretical courses are taught in semester-long classrooms with full attendance. Practical sessions are held in the Anatomy Model Room and the Basic Medical Sciences Laboratories.

Objectives of the Course

In this course:
• The developmental, macroscopic, and microscopic structural and functional characteristics of the structures comprising the circulatory and respiratory systems and the immune system;
• The detailed development of structures belonging to the cardiovascular, respiratory, and hematopoietic systems, as well as their structural characteristics at the cellular and tissue levels;
• Detailed information regarding their functions in light of physiological, biochemical, and biophysical knowledge.

Contribution of the Course to Field Teaching

Basic Vocational Courses	X
Specialization / Field Courses
Support Courses
Transferable Skills Courses	X
Humanities, Communication and Management Skills Courses

Relationships between Course Learning Outcomes and Program Outcomes

Relationship Levels
Lowest	Low	Medium	High	Highest
1	2	3	4	5

#	Program Learning Outcomes	Level
P1	Applies knowledge and skills in basic, clinical, and behavioral medical sciences using a comprehensive approach in the patient care process.	3
P2	Explains the anatomical, histological, physiological, and biochemical characteristics of the systems that make up the human body, relating them to clinical practice.	3
P3	Uses medical terminology accurately and effectively in clinical, academic, and professional communication.	3
P4	In accordance with evidence-based medicine and good medical practice, they take a medical history, perform a physical examination, and develop a clinical approach for the patient.	5
P5	Performs basic medical procedures—such as measuring blood pressure, establishing intravenous access, drawing blood, and administering injections—using appropriate techniques.	5
P6	Evaluates the etiology and pathogenesis, clinical findings, and key diagnostic features of common diseases.	3
P7	The laboratory interprets microbiological, imaging, and histopathological findings by correlating them with clinical processes.	5
P8	Explains and, when appropriate, applies pharmacological, physical, and psychosocial treatment approaches tailored to the characteristics of the disease.	5

Course Learning Outcomes

Upon the successful completion of this course, students will be able to:
No	Learning Outcomes	Outcome Relationship	Measurement Method **
O1	It explains the anatomical, histological, physiological, and biochemistry characteristics of the systems that make up the human body by relating them to clinical practice.	P.1.1	1,7
O2	Has a command of current medical terminology.	P.1.2	1,4
O3	Apply basic medical skills such as blood pressure measurement, blood collection, injection and evaluate them critically.	P.1.4	1,4
O4	Adopts that the primary duty of the physician is to protect human life and health by taking preventive measures against diseases.	P.3.1	1,4
O5	Recognize their deficiencies in terms of medical skills and knowledge and overcome them with up-to-date information.	P.4.4	1,4
O6	Utilizes medical information and communication technologies.	P.6.3	1,4
O7	Defines and uses appropriate terms in a foreign language in the field of medicine.	P.7.3	1,4
O8	Approach patients and their relatives regardless of age, illness or disability, belief, ethnicity, gender, location, and recognize this as an ethical obligation.	P.8.1	1,7
** Written Exam: 1, Oral Exam: 2, Homework: 3, Lab./Exam: 4, Seminar/Presentation: 5, Term Paper: 6, Application: 7

Weekly Detailed Course Contents

Week	Topics
1	Introduction to the Circulatory System Heart Anatomy and Pericard Head and Neck Veins Introduction to Blood Physiology Plasma Proteins Cardiovascular System Development and Anomalies Cardiovascular Histology Head, Neck and Facial Development Blood Tissue Plasma Proteins Plasma Protein Electrophoresis Clinical Use of Plasma Proteins Biological Buffer System
2	Body Veins Blood Making (Hematopoiesis) Functions of Erythrocytes Hemoglobin Structure and Functions Anemia, Polycythemia Functions of Platelets Hemostasis Mechanisms hematopoiesis Platelet and Coagulation Biochemistry Introduction to the immune system natural immunity Humoral Immune Responses Cell Mediated Immune Responses
3	Upper Extremity Veins Lower Extremity Veins veins action potential in cardiac cells Biophysical Fundamentals of EKG Coagulation Mechanisms Anticoagulation Mechanisms and Coagulation Disorders Leukocytes and immune system Functions Antigen Collection and Presentation to Lymphocytes Antigen Recognition in the Acquired Immune System Effective Mechanisms of Humoral Immunity Functional Mechanisms of Cellular Immunity Hypersensitivity Reactions Congenital and Acquired Immune Deficiencies
4	Lymphatic System, Spleen, Thymus Fetal Circulation Circulating Hydrostatic Factor and Internal Frictional Flow, Coefficient of Viscosity and Eddy Flow Physiological Characteristics of the Heart Muscle Heart's Warning Message System Regulation of Heart Function ECG Heart Cycle Heart Valves and Heart Sounds Thymus Lymph Node and Spleen Coagulation Regulation and Fibrinolytic System Both Synthesis and Metabolism of Porphyrin Bilirubin Metabolism Erythrocyte, Leukocyte and Platelet Biochemistry Immunological Tolerance and Autoimmunity Immune Responses to Tumors Transplantation Immunolog
5	Solunum Sistemine Giriş - Burun Boşluğu Damar Genişleyebilirliği ve Laplace Yasası Solunum Dinamiği Sistemik Dolaşımın Genel Özellikleri Kan Akımı Direnç ve Basınç İlişkisi Arteryel ve Venöz Sistemlerin İşlevleri Dokularda Kan Akımının Düzenlenmesi Dolaşımın Hümoral Faktörlerle Düzenlenmesi Mikrodolaşım ve Lenfatik Sistem Kan Basıncı ve Nöronal Mekanizmalarla Düzenlenmesi Böbrekler ve Renin, Anjiyotensin Sisteminin İşlevleri Hipertansiyonun Fizyopatolojik Mekanizmaları Kalp Debisi ve Venöz Dönüş Koroner Dolaşım ve Koroner Arter Hastalığı Fizyopatolojisi Endotel ve İşlevleri Üst Solunum Yolu Histolojisi Trakea ve Akciğerlerin Gelişimi Aktif ve Pasif Bağışıklama
6	Paranasal Sinus larynx Functional Anatomy and General Features of the Respiratory System
7	trachea Lung -Pleura, Mediastinum Respiratory Muscles Mechanics of Breathing and Pulmonary Ventilation Compliance of the Lungs Alveolar Ventilation Lung Volumes and Capacities Features of Pulmonary Circulation Factors Affecting Pulmonary Vascular Resistance Regional Distribution of Blood Flow in the Lungs Ventilation Perfusion Rate Partial Pressures of Gases in the Airways and Blood Forces Determining Diffusion of Gases at Alveolar and Tissue Level Transport of Oxygen and Carbon Dioxide in the Blood Oxygen Dissociation Curve Central and Peripheral Control of Respiration Exercise Physiology Lower Airway Histology Clinical Embryology
8	EXAM WEEK

Textbook or Material

Resources	Biochemistry (Prof.Dr. Figen Gürdöl, Assoc.Dr.Evin Ademoğlu, Nobel Medical Bookstore)
	Anatomy. Prof. Dr. Kaplan ARINCI, Prof. Dr. Alaittin ELHAN. 2006. Güneş Bookstore
	Lehninger Principles of Biochemistry (David L. Nelson Michael M. Cox, Palme Publishing)
	Physiology Human Physiology. Prof.Dr. Erdal AĞAR, Istanbul Medical Bookstores, 2020
	Anatomy atlas and textbook. Prof. Dr. Fahri DERE. 2010. Nobel Medicine Bookstore
	Color Text Book of Histology. Second ed. SAUNDERS
	Langman's Medical Embryology, Eleventh Edition. Lippincott Williams & Wilkins, USA 6 Schoenwolf G.C
	Larsen's Human Embryology. 4. Ed. CHURCHILL LIVINGSTONE ELSEVIER
	Human Embryology with Clinical Aspects. 6th Ed. NOBEL TIP 8 Junqueira L.C., Carneiro J. Transl. Ed: Aytekin Y, Solakoglu S
	Basic Histology NOBEL MEDICINE
	Color Atlas of Histology, Fifth Edition. Lippincott Williams & Wilkins, USA
	Sobotta Atlas of Histology. BETA
	Langman's Medical Embryology, Eleventh Edition. Lippincott Williams & Wilkins, USA
	Human Biochemistry (Prof.Dr.Taner Onat-Prof.Dr.Kaya Emerk, Palme Publishing)
	Medical Physiology, Guyton – Hall
	Clinical Anatomy, Snell
	Biochemistry, Montgomery - Conwey – Spector
	Histology: A Text and Atlas, Ross – Kaye – Pawlina
	Sobotta Atlas of Human Anatomy (3 Volume Set). J. Sobotta. 2015. Beta publications. (Translation editor: Prof. Dr. Alaittin ELHAN)
	Physiology. Nobel Medical Bookstores Ganong's Medical Physiology - Susan M. Barman, 1st Edition,2018
	Biochemistry Explained Question and Answer, Prof.Dr. Kadirhan Sunguroğlu, Akademi Publishing)
	Harper Biochemistry, Robert Murray, Nobel Medical Bookstore)
	Professional skills laboratory materials. Patient-physician relationship sheets organised for patient-physician relationships. Drama sheets organised for patient-physician relations Visits to places where community health services are provided

Evaluation Method and Passing Criteria

In-Term Studies	Quantity	Percentage
Attendance	-	-
Laboratory	-	-
Practice	-	-
Course Specific Internship (If Any)	-	-
Midterms	1	100 (%)
Final Exam	-	-
Total		100 (%)

ECTS / Working Load Table

	Quantity	Duration	Total Work Load
Course Week Number and Time	6	28	168
Out-of-Class Study Time (Pre-study, Library, Reinforcement)	1	38	38
Midterms	1	46	46
Quiz	0	0	0
Homework	0	0	0
Practice	0	0	0
Laboratory	6	8	48
Project	0	0	0
Workshop	0	0	0
Presentation/Seminar Preparation	0	0	0
Fieldwork	0	0	0
Final Exam	1	60	60
Other	0	0	0
Total Work Load:			360
Total Work Load / 30			12
Course ECTS Credits:			12

Course - Learning Outcomes Matrix

Relationship Levels
Lowest	Low	Medium	High	Highest
1	2	3	4	5

#	Learning Outcomes	P1	P3	P4	P6	P7	P8
O1	It explains the anatomical, histological, physiological, and biochemistry characteristics of the systems that make up the human body by relating them to clinical practice.	5	-	-	-	-	-
O2	Has a command of current medical terminology.	4	-	-	-	-	-
O3	Apply basic medical skills such as blood pressure measurement, blood collection, injection and evaluate them critically.	5	-	-	-	-	-
O4	Adopts that the primary duty of the physician is to protect human life and health by taking preventive measures against diseases.	-	4	-	-	-	-
O5	Recognize their deficiencies in terms of medical skills and knowledge and overcome them with up-to-date information.	-	-	4	-	-	-
O6	Utilizes medical information and communication technologies.	-	-	-	4	-	-
O7	Defines and uses appropriate terms in a foreign language in the field of medicine.	-	-	-	-	3	-
O8	Approach patients and their relatives regardless of age, illness or disability, belief, ethnicity, gender, location, and recognize this as an ethical obligation.	-	-	-	-	-	5