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Course Details
KTO KARATAY UNIVERSITY
Medical School
Programme of Faculty of Medicine
Course Details
Course Code Course Name Year Period Semester T+A+L Credit ECTS
KURUL14 Cartilage, Bone and Connective Tissues 2025 Autumn 1 89+38+38 10 10
Course Type Compulsory
Course Cycle Bachelor's (First Cycle) (TQF-HE: Level 6 / QF-EHEA: Level 1 / EQF-LLL: Level 6)
Course Language Turkish
Methods and Techniques In the course committee, theoretical lectures, question-and-answer sessions, and active participation methods are used. In practical training, laboratory practices, examination of anatomical models/bones, evaluation of histology preparations, genetics laboratory practices, demonstration and practice, and self-study techniques are included. In addition, students'active learning processes are supported through evidence-based medicine practices, individual study, and practice-based learning methods.
Mode of Delivery Face to Face
Prerequisites Herhangi bir ön koşul aranmamaktadır.
Coordinator Asst. Prof. Tuğçe DURAN
Instructor(s) Assoc. Prof. Tuğçe DURAN
Instructor Assistant(s) -
Course Instructor(s)
Name and Surname Room E-Mail Address Internal Meeting Hours
Asst. Prof. Şerife ALPA B-Z02 [email protected] 7411 Thursday
11:00-12:00
Derya Işıklar ÖZBERK -
Assoc. Prof. Tuğçe DURAN B-Z05 [email protected] 7237 Tuesday
10:30-11:30
Asst. Prof. Hatice Nur ŞEFLEK B-Z06 [email protected] 7583 Monday
10:00-11:00
Assoc. Prof. Gülben AKCAN B-Z06 [email protected] 7503 Monday
14:00-15:00
Asst. Prof. Füsun SUNAR B-Z08 [email protected] 0000
Asst. Prof. Levent SARIYILDIZ B-Z12 [email protected] 7311 Thursday
11:00-12:00
Asst. Prof. Hatice Nur ŞEFLEK B-Z06 [email protected] 7583 Monday
10:00-11:00
Course Content
The course committee content covers the skeletal system, general characteristics of bones, bones of the upper and lower extremities, columna vertebralis, thoracic bones, neurocranium, viscerocranium, and the entire cranial skeleton. Within the scope of the committee, the anatomical structures and locations of bones, the formations on them, and their functions within the locomotor system are addressed.

The course content includes the examination of the basic histological characteristics of epithelial tissue, covering and glandular epithelia, connective tissue, adipose tissue, cartilage tissue, and bone tissue. In addition, fundamental biochemical topics such as mineral metabolism, electrolytes, iron metabolism, trace elements, calcium-phosphorus metabolism, and the biochemistry of bone tissue are included.

Throughout the committee, students acquire knowledge about genetic topics and applications such as chromosomal abnormalities, cytogenetic and molecular cytogenetic methods, recombinant DNA technology, genetic counseling, personalized medicine, DNA isolation from blood, PCR, gel electrophoresis, restriction enzyme digestion, and the RFLP technique. In addition, evidence-based medicine practices, scientific authorship, selection of articles appropriate to the aim, and the development of evidence-based medicine are also included within the course content.
Objectives of the Course
The aim of the course committee is to enable students to acquire fundamental knowledge about the anatomical, histological, biochemical, and genetic characteristics of cartilage, bone, and connective tissues. Within this scope, students are expected to learn the bones that constitute the skeletal system, their locations, anatomical structures, and functions within the locomotor system.

During the committee process, students are expected to comprehend the basic structural characteristics, classification, and distinguishing features of epithelial, connective, cartilage, bone, and adipose tissues. In addition, it is aimed that students learn topics such as mineral metabolism, electrolytes, iron metabolism, calcium-phosphorus metabolism, trace elements, and the biochemistry of bone tissue.

The course committee also aims to provide students with fundamental knowledge about chromosomal abnormalities, cytogenetic methods, recombinant DNA technology, personalized medicine, genetic counseling, and molecular genetic applications. Furthermore, through topics such as scientific authorship, article selection, and evidence-based medicine, it is aimed to develop students'scientific thinking and academic evaluation skills.
Contribution of the Course to Field Teaching
Basic Vocational Courses X
Specialization / Field Courses X
Support Courses
Transferable Skills Courses
Humanities, Communication and Management Skills Courses
Relationships between Course Learning Outcomes and Program Outcomes
Relationship Levels
Lowest Low Medium High Highest
1 2 3 4 5
# Program Learning Outcomes Level
P1 Has basic and clinical medical knowledge. 3
P2 Has the professional skills required for diagnosis, diagnosis and treatment. 2
P3 Knows and applies the basic principles for protecting and improving individual and community health. 2
P4 Assumes responsibility for lifelong learning and makes self-assessment. 3
P5 Work effectively individually and as a team. 4
P6 Uses information technologies effectively, especially the current tools required in the field of medicine. 3
P7 Communicates effectively both orally and in writing. 3
P8 Acts in accordance with professional values, ethical principles and legal regulations. 3
Course Learning Outcomes
Upon the successful completion of this course, students will be able to:
No Learning Outcomes Outcome Relationship Measurement Method **
O1 Knows the anatomical, histological, physiological and biochemical properties of the systems that make up the body and can apply basic experimental studies. P.1.1 1,7
O2 Has a command of current medical terminology. P.1.2 1
O3 Know the biochemical and microbiological laboratory results, medical imaging and histopathological findings of diseases. P.1.6 1,7
** Written Exam: 1, Oral Exam: 2, Homework: 3, Lab./Exam: 4, Seminar/Presentation: 5, Term Paper: 6, Application: 7
Weekly Detailed Course Contents
Week Topics
1 General Information About Bones Upper Limb Bones (Scapula-Clavicula) Upper Extremity Bones (Humerus-Radius-Ulna-Manus) Basic Properties and Classification of Epithelial Tissues Meiosis and mitosis and genome relationship Chromosome packaging of DNA Chromosome abnormalities and classification Mechanisms of chromosomal abnormalities Scientific Authorship
2 Columna Vertebralis Thorax Bones Lower Limb Bones Covering and Secretory Epithelia Connective tissues and intercellular substance Medical importance of chromosomal abnormalities Chromosome abnormalities detection (cytogenetic) methods Appropriate Article Selection History and Development of Evidence-Based Medicine Introduction to Mineral Metabolism Electrolytes Iron Metabolism
3 Lower Limb Bones Neurocranium Bones Submicroscopic (Molecular cytogenetic anomalies) Recombinant DNA technology and its applications in medicine Bone and Cartilage Tissues Calcium and Phosphorus Metabolism
4 Neurocranium Bones Viscerocranium Bones Individual medicine, genetic counseling and preventive medicine Bone Tissue Biochemistry
5 Trace Elements Viscerocranium Bones Whole Skull Skeleton
6 Viscerocranium Bones Recombinant DNA Technology and Transformation
7 Exam week
Textbook or Material
Resources Anatomy. Prof. Dr. Kaplan ARINCI, Prof. Dr. Alaittin ELHAN. 2006. Güneş Bookstore. Sobotta Atlas of Human Anatomy (3 Volume Set). J. Sobotta. 2015. Beta releases. (Translation editor: Prof. Dr. Alaittin ELHAN).Netter Atlas of Human Anatomy. Frank H. Netter. 2015. Nobel Medical Bookstore. (Translation editor: Prof. Dr. Meserret Cumhur). Anatomy atlas and textbook. Prof. Dr. Fahri DERE. 2010. Nobel Medical Bookstore.
Genetic Concepts, W.S.Klug, M.R.Cumming, Palme Publishing Medical Biology and Genetics Prof.Dr H. Kasap, Prof. Dr. M. Kasap.Nobel Medicine Bookstore Medical Genetics Prof.Dr.N. Başaran Nobel Medical Bookstore Medical Biology Prof.Dr.M. Çarin, Prof.Dr.F. Aydın Nobel Medical Bookstore Prof. Dr Ayşe Başaran, Pelikan Publishing
Histological staining techniques, Prof.Dr.Ramazan DEMİR, Palme publishing Junqueiras basic histology text atlas, Anthony, Nobel medicine Ross M.: Histology: A Text and Atlas, Gartner L.P., Hiatt J.L.: Color Text Book of Histology. Second ed. SAUNDERS Histology: A Text and Atlas: With Correlated Cell and Molecular Biology, Michael H. Ross
Evaluation Method and Passing Criteria
In-Term Studies Quantity Percentage
Attendance 6 80 (%)
Laboratory 3 18 (%)
Practice 1 2 (%)
Course Specific Internship (If Any) - -
Midterms 1 40 (%)
Final Exam 1 60 (%)
Total 200 (%)
ECTS / Working Load Table
Quantity Duration Total Work Load
Course Week Number and Time 6 19 114
Out-of-Class Study Time (Pre-study, Library, Reinforcement) 1 22 22
Midterms 1 55 55
Quiz 0 0 0
Homework 0 0 0
Practice 0 0 0
Laboratory 4 10 40
Project 0 0 0
Workshop 0 0 0
Presentation/Seminar Preparation 0 0 0
Fieldwork 0 0 0
Final Exam 1 70 70
Other 0 0 0
Total Work Load: 301
Total Work Load / 30 10,03
Course ECTS Credits: 10
Course - Learning Outcomes Matrix
Relationship Levels
Lowest Low Medium High Highest
1 2 3 4 5
# Learning Outcomes P1
O1 Knows the anatomical, histological, physiological and biochemical properties of the systems that make up the body and can apply basic experimental studies. 5
O2 Has a command of current medical terminology. 4
O3 Know the biochemical and microbiological laboratory results, medical imaging and histopathological findings of diseases. 5